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No on all 3 Human pharmacokinetics and bioavailability are unknown So, commonly promoted dosing protocols are essentially guesses We do not know how much reaches circulation, how long it stays active in humans, what dose works for what indication, and what the long-term risks are, or what would even need to be monitored The absence of an obvious safety signal is not evidence of safety Phase 1 clinical trials to pick up safety signals haven’t been run Long-term and repeated dose effects have not been adequately studied A practical safety framework should tell us how to use the molecule safety, what to watch for, and how to intervene if something goes wrong BPC-157 doesn’t give us any of that Question #4: Does the likely benefit justify the risk for this person