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Additionally, during the CORT process, the number and structural abnormalities of GR (excessive beta structure and insufficient alpha structure) and imbalanced expression of 11β-HSD (excessive 11β-HSD1 and insufficient 11β-HSD2) prevent the anti-inflammatory effects of CORT, contributing to GC resistance in immunotherapy
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[DOI] [PubMed] [Google Scholar] 11.Doessing S., Heinemeier K.M., Holm L., Mackey A.L., Schjerling P., Rennie M., Smith K., Reitelseder S., Kappelgaard A.M., Rasmussen M.H., et al
