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PERG recordings were obtained using high-resolution electroretinography, capturing retinal responses to counterphased horizontal gratings

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and decreasing the levels of CutC and TMAO, leading to the attenuation of the TMAO-induced phosphorylation of ERK1/2 and JNK in platelets and reduced platelet reactivity to collagen and risk of atherothrombosis (Xie et al., 2021)