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doi: 10.3389/fphar.2021.622498 Received 28 October 2020 Accepted 11 June 2021 Published 24 June 2021 Volume 12 - 2021 Edited by Uraiwan Panich, Mahidol University, Thailand Reviewed by Mingjiang Yao, Xiyuan Hospital, China Rodrigo Castaneda, Universidad de San Carlos de Guatemala, Guatemala Updates Copyright © 2021 Tian, Huang, Wu, Huang, Ko, Zhu and Chen