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Second, the strength of tirzepatide’s evidence is exactly what makes an apples-to-apples ranking against an investigational amylin analog impossible: you cannot fairly rank a fully-approved drug against a candidate whose stand-alone efficacy stops at Phase 2
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High-dose (≥45 mg/day) iron supplements can cause gastrointestinal side effects, including nausea, constipation, vomiting, and diarrhea (181)
