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Tolerogenic peptide therapy aims instead to induce immune tolerance to self-antigens by selectively targeting and suppressing self-reactive T cells, while promoting the expansion of regulatory T cells (T regs ) and tolerogenic dendritic cells (DCs)

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Analysis using the Broad Institute’s Connectivity Map database identified GHK as one of the top two compounds (from 1,309 bioactive molecules screened) recommended for study in aggressive metastatic colon cancer models