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In contrast, an overproduction of ROS, outstripping the scavenging capacity of antioxidants, leads to oxidative stress, contributing to stone development ( The origins of ROS within the human body are multifarious, entailing the involvement of an array of signaling pathways

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469 In contrast, the liver and serum NAMPT of morbidly obese women with NAFLD are significantly higher than that of morbidly obese women with healthy livers